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顶部生物活性储存和溶解信息计算器

Anti-XRCC5 Antibody (9O180)

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Anti-XRCC5 Antibody (9O180)
产品编号 TMAC-02347
别名 CTC-85

Anti-XRCC5 Antibody (9O180) 是一种 Rabbit 抗体，靶向 XRCC5。Anti-XRCC5 Antibody (9O180) 可用于 WB,ICC/IF,IHC,IP。

Anti-XRCC5 Antibody (9O180)

Anti-XRCC5 Antibody (9O180)

Rating icon 还可以
Anti-XRCC5 Antibody (9O180)
产品编号 TMAC-02347 别名 CTC-85

Anti-XRCC5 Antibody (9O180) 是一种 Rabbit 抗体，靶向 XRCC5。Anti-XRCC5 Antibody (9O180) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-XRCC5 Antibody (9O180) is a Rabbit antibody targeting XRCC5. Anti-XRCC5 Antibody (9O180) can be used in WB,ICC/IF,IHC,IP.
别名CTC-85
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of Ku80 on MCF-7 cells lysates using anti-Ku80 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Ku80 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kideny tissue using anti-Ku80 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Ku80 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Ku80 antibody. Counter stained with hematoxylin.
6. ICC staining Ku80 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining Ku80 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining Ku80 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
IP
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (p70) and Ku-86 (p86) which is also known by the synonym Ku-80 or (p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation. Ku is involved in Pol II-directed transcription by virtue of its DNA binding activity, serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters. A Ku-related protein designated the enhancer 1 binding factor (E1BF), composed of two subunits, has been identified as a positive regulator of RNA polymerase I transcription initiation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P13010
化学信息
分子量Theoretical: 83 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

XRCC5XRCC 5X-ray repair cross-complementing protein 5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)TLAAThyroid-lupus autoantigen (TLAA)Nuclear factorIVNuclear factor IVLupus Ku autoantigen protein p86Ku86Ku80Ku 86Ku 80G22P2G22P 2double-strand-break rejoiningDNA repair protein XRCC5CTCBF)CTC85CTC box-binding factor 85 kDa subunit (CTC85ATP-dependent DNA helicase II 80 kDa subunitATP-dependent DNA helicase 2 subunit 286 kDa subunit of Ku antigen

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