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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FKRP Polyclonal Antibody

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货号 TMAB-06052

Anti-FKRP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FKRP。Anti-FKRP Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-FKRP Polyclonal Antibody

Anti-FKRP Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06052

Anti-FKRP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FKRP。Anti-FKRP Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-FKRP Polyclonal Antibody is a Rabbit antibody targeting FKRP. Anti-FKRP Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Golgi apparatus. Secreted. Cell membrane > sarcolemma. Rough endoplasmic reticulum. According to some studies the N-terminal hydrophobic domain is cleaved after translocation to the Golgi apparatus and the protein is secreted. According to others the N-terminal hydrophobic domain is a transmembrane domain and the protein is a type II transmembrane type targeted to the Golgi apparatus by a non-cleavable signal anchor sequence. Localization at the cell membrane may require the presence of dystroglycan. At the Golgi apparatus localizes most likely at the cis-compartment. Detected in rough endoplasmic reticulum in myocytes. In general, mutants associated with severe clinical phenotypes are retained within the endoplasmic reticulum.
组织特异性Expressed predominantly in skeletal muscle, placenta, and heart and relatively weakly in brain, lung, liver kidney and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in this gene have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human FKRP
抗原种属
Human
基因名称
FKRP
基因ID
79147
蛋白名称
Fukutin-related protein
Uniprot ID
Q9H9S5
功能
Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1).
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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