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Anti-PPP3CA Polyclonal Antibody 2

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货号 TMAB-11690

Anti-PPP3CA Polyclonal Antibody 2 是一种 Mouse 抗体，靶向 PPP3CA。Anti-PPP3CA Polyclonal Antibody 2 可用于 FCM。

Anti-PPP3CA Polyclonal Antibody 2

Anti-PPP3CA Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-11690

Anti-PPP3CA Polyclonal Antibody 2 是一种 Mouse 抗体，靶向 PPP3CA。Anti-PPP3CA Polyclonal Antibody 2 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PPP3CA Polyclonal Antibody 2 is a Mouse antibody targeting PPP3CA. Anti-PPP3CA Polyclonal Antibody 2 can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用FCM
推荐剂量
FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Mouse
亚细胞定位Nucleus. Note=Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.
组织特异性Interacts with CHP1 and CHP2. Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with CRTC2, MYOZ1, MYOZ2 and MYOZ3. Interacts with DNM1L; the interaction dephosphorylates DNM1L and regulates its translocation to mitochondria. Interacts with CMYA5; this interaction represses calcineurin activity in muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Calcineurin, a major soluble calmodulin binding protein in the brain, a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively narrow substrate specificity. This metalloenzyme, also known as phosphatase 2B, is a heterodimer composed of a calmodulin binding, catalytic alpha subunit 61 kDa, calcineurin A) and calcium binding beta subunit (18 kDa, calcineurin B). The Ca2+ binding subunit, calcineurin B, is immunologically conserved from yeast to mammals. The presence of 2 different calcineurin B isoforms (beta 1 and beta 2) has been reported in rat testis. The catalytic subunit of calcineurin, calcineurin A, isolated from different tissues or different organisms, exhibits some immunological heterogeneity. Further, there are at least 2 isoforms of calcineurin A in bovine brain (alpha 1 and alpha 2, 61 and 59 kDa, respectively).
抗原信息
免疫原
KLH conjugated synthetic peptide: human PPP3CA
抗原种属
Human
基因名称
PPP3CA
基因ID
5530
蛋白名称
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Uniprot ID
Q08209
功能
Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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