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Anti-GP1BA Polyclonal Antibody

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货号 TMAB-06647

Anti-GP1BA Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GP1BA。Anti-GP1BA Polyclonal Antibody 可用于 WB。

Anti-GP1BA Polyclonal Antibody

Anti-GP1BA Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06647

Anti-GP1BA Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GP1BA。Anti-GP1BA Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-GP1BA Polyclonal Antibody is a Rabbit antibody targeting GP1BA. Anti-GP1BA Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010].
抗原信息
免疫原
KLH conjugated synthetic peptide: human GP1BA/CD42b
抗原种属
Human
基因名称
GP1BA
基因ID
蛋白名称
Platelet glycoprotein Ib alpha chain
Uniprot ID
功能
GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.
化学信息
分子量Theoretical: 67 kDa. Actual: 145 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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