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Anti-COMP Antibody (1M696)

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产品编号 TMAY-00402

Anti-COMP Antibody (1M696) 是一种 Mouse 抗体,靶向 COMP。Anti-COMP Antibody (1M696) 可用于 ELISA,ELISA(Cap)。

Anti-COMP Antibody (1M696)

Anti-COMP Antibody (1M696)

Rating icon 还可以
产品编号 TMAY-00402

Anti-COMP Antibody (1M696) 是一种 Mouse 抗体,靶向 COMP。Anti-COMP Antibody (1M696) 可用于 ELISA,ELISA(Cap)。

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产品介绍

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产品描述
Anti-COMP Antibody (1M696) is a Mouse antibody targeting COMP. Anti-COMP Antibody (1M696) can be used in ELISA,ELISA(Cap).
Ig Type
Monoclonal Mouse IgG1
克隆号
1M696
交叉反应
Human
应用
ELISA,ELISA(Cap)
推荐剂量
ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human COMP (rhCOMP; TMPY-00725; NP_000086.2; Met 1-Ala 757). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Cartilage Oligomeric Matrix Protein (COMP), also referred to as Thrombospondin-5, is a non-collagenous extracellular matrix (ECM) protein and belongs to the subgroup B of the thrombospondin protein family. This protein is expressed primarily in cartilage, ligament, and tendon, and binds to other ECM proteins such as collagen I, II and IX with high affinities depending on the divalent cations Zn2+ or Ni2+. COMP is a secreted glycoprotein that is important for growth plate organization and function. It is suggested to play a role in cell growth and development, and recent studies have revealed the possible mechanism that it protects cells against death by elevating members of the IAP (inhibitor of apoptosis protein) family of survival proteins. Mutations in COMP cause two skeletal dysplasias, pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (EDM1), and up-regulated expression of COMP are observed in rheumatoid arthritis and certain carcinomas.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
HRP
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human COMP protein (TMPY-00725)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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