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IFN-alpha 2b/IFNA2 Protein, Human, Recombinant

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SPR兼容缓冲液

纯度: 99.9%

货号 TMPJ-00746

别名 干扰素, LeIF A, Interferon α-A, Interferon α-2, Interferon Alpha-A, Interferon Alpha-2, IFN-α-2, IFN-Alpha-2, IFNA2, IFN α2b

At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end.

IFN-alpha 2b/IFNA2 Protein, Human, Recombinant

IFN-alpha 2b/IFNA2 Protein, Human, Recombinant

一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液

纯度: 99.9%

货号 TMPJ-00746 别名 干扰素, LeIF A, Interferon α-A, Interferon α-2, Interferon Alpha-A, Interferon Alpha-2, IFN-α-2, IFN-Alpha-2, IFNA2, IFN α2b

At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end.

规格价格库存数量
5 μg
¥ 243
3日内发货
10 μg
¥ 380
现货
20 μg
¥ 590
现货
50 μg
¥ 1,090
现货
100 μg
¥ 1,470
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纯度: Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
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产品介绍


生物活性
产品描述
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end.
生物活性
1. Loaded Human IFNAR2-Fc on Protein A Biosensor, can bind Human IFN alpha2b with an affinity constant of 2.98 nM as determined in BLI assay. (Regularly tested) 2. Measured in antiviral assay using A549 human lung cancer cells infected with vesicular stomatitisvirus (VSV) The ED50 for this effect is 5 ng/mL. (Regularly tested)
IFN-alpha 2b/IFNA2 Protein, Human, RecombinantIFN-alpha 2b/IFNA2 Protein, Human, Recombinant
研究背景
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end.
种属
Human
表达系统
E. coli
标签Tag Free
蛋白编号P01563
氨基酸序列Cys24-Glu188
蛋白构建Cys24-Glu188
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
IFN-alpha 2b/IFNA2 Protein, Human, RecombinantIFN-alpha 2b/IFNA2 Protein, Human, Recombinant
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.2.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名干扰素, LeIF A, Interferon α-A, Interferon α-2, Interferon Alpha-A, Interferon Alpha-2, IFN-α-2, IFN-Alpha-2, IFNA2, IFN α2b
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量17 KDa (reducing condition)
颜色White
物理性状Lyophilized powder
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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