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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CLSTN1 Antibody (7F653)

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货号 TMAB-04469

Anti-CLSTN1 Antibody (7F653) 是一种 Rabbit 抗体，靶向 CLSTN1。Anti-CLSTN1 Antibody (7F653) 可用于 FCM, IF, IHC-Fr, IHC-P, WB。

Anti-CLSTN1 Antibody (7F653)

Anti-CLSTN1 Antibody (7F653)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04469

Anti-CLSTN1 Antibody (7F653) 是一种 Rabbit 抗体，靶向 CLSTN1。Anti-CLSTN1 Antibody (7F653) 可用于 FCM, IF, IHC-Fr, IHC-P, WB。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

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产品描述
Anti-CLSTN1 Antibody (7F653) is a Rabbit antibody targeting CLSTN1. Anti-CLSTN1 Antibody (7F653) can be used in FCM, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
克隆号
7F653
反应种属
Human,Mouse,Rat
应用FCMIFIHC-FrIHC-PWB
推荐剂量
FCM=1:50-100; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell projection. Cell junction > synapse > postsynaptic cell membrane. Nucleus. Neurite tips. Localized in the postsynaptic membrane of both excitatory and inhibitory synapses (By similarity). The AlcICD fragment is translocated to the nucleus upon interaction with APBB1.
组织特异性Expressed in the brain and, a lower level, in the heart, skeletal muscle, kidney and placenta. Accumulates in dystrophic neurites around the amyloid core of Alzheimer disease senile plaques (at protein level).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation. Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane.
抗原信息
免疫原
A synthesized peptide: human Calsyntenin 1
抗原种属
Human
基因名称
CLSTN1
基因ID
22883
蛋白名称
Calsyntenin-1
Uniprot ID
O94985
功能
Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals.
化学信息
分子量Theoretical: 110 kDa. Actual: 150 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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