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UBE2K Protein, Human, Recombinant (GST)

UBE2K Protein, Human, Recombinant (GST)

产品编号 TMPJ-01038
别名: Ubiquitin-Conjugating Enzyme E2(25K), Ubiquitin Carrier Protein, Ubiquitin-Conjugating Enzyme E2-25K, HIP-2, Ubiquitin-Protein Ligase, Ubiquitin-Conjugating Enzyme E2-25 kDa, HIP2, Huntingtin-Interacting Protein 2, UBE2K, Ubiquitin-Conjugating Enzyme E2 K

UBE2K Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 45 KDa and the accession number is P61086.

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UBE2K Protein, Human, Recombinant (GST)
规格 价格/CNY 货期 数量
10 μg ¥ 220 5日内发货
50 μg ¥ 580 5日内发货
500 μg ¥ 4,970 5日内发货
1 mg ¥ 7,110 5日内发货
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产品目录号及名称: UBE2K Protein, Human, Recombinant (GST) (TMPJ-01038)
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产品描述 UBE2K Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 45 KDa and the accession number is P61086.
种属 Human
表达系统 E. coli
标签 N-GST
蛋白编号 P61086
别名 Ubiquitin-Conjugating Enzyme E2(25K), Ubiquitin Carrier Protein, Ubiquitin-Conjugating Enzyme E2-25K, HIP-2, Ubiquitin-Protein Ligase, Ubiquitin-Conjugating Enzyme E2-25 kDa, HIP2, Huntingtin-Interacting Protein 2, UBE2K, Ubiquitin-Conjugating Enzyme E2 K
氨基酸序列 Met1-Asn200
蛋白构建 Met1-Asn200
分子量 45 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain, with highest levels found in cortex and striatum, and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition, UBE2K is involved in Alzheimer's disease, Huntington's disease and antigen processing through its interaction with huntingtin, and MHC-heavy chain proteins.

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Keywords

UBE2K Protein, Human, Recombinant (GST) Ubiquitin-Conjugating Enzyme E2(25K) Ubiquitin Carrier Protein Ubiquitin-Conjugating Enzyme E2-25K HIP-2 Ubiquitin-Protein Ligase Ubiquitin-Conjugating Enzyme E2-25 kDa HIP2 Huntingtin-Interacting Protein 2 UBE2K Ubiquitin-Conjugating Enzyme E2 K HIP 2 recombinant recombinant-proteins proteins protein

 

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