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Anti-hydrogen exchanger 3 Polyclonal Antibody 3

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货号 TMAB-07465

Anti-hydrogen exchanger 3 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 hydrogen exchanger 3。Anti-hydrogen exchanger 3 Polyclonal Antibody 3 可用于 WB。

Anti-hydrogen exchanger 3 Polyclonal Antibody 3

Anti-hydrogen exchanger 3 Polyclonal Antibody 3

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Rating icon 还可以
货号 TMAB-07465

Anti-hydrogen exchanger 3 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 hydrogen exchanger 3。Anti-hydrogen exchanger 3 Polyclonal Antibody 3 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-hydrogen exchanger 3 Polyclonal Antibody 3 is a Rabbit antibody targeting hydrogen exchanger 3. Anti-hydrogen exchanger 3 Polyclonal Antibody 3 can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane. In intestinal epithelial cells, localizes to the ileal brush border.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human hydrogen exchanger 3
抗原种属
Human
基因名称
SLC9A3
基因ID
6550
蛋白名称
Sodium/hydrogen exchanger 3
Uniprot ID
P48764
功能
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
化学信息
分子量Theoretical: 93 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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