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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FGF-23 Polyclonal Antibody

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货号 TMAB-00671

别名 Fibroblast growth factor 23, FGF-23, Fgf23

Anti-FGF-23 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FGF-23。Anti-FGF-23 Polyclonal Antibody 可用于 WB。

Anti-FGF-23 Polyclonal Antibody

Anti-FGF-23 Polyclonal Antibody

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货号 TMAB-00671 别名 Fibroblast growth factor 23, FGF-23, Fgf23

Anti-FGF-23 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FGF-23。Anti-FGF-23 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-FGF-23 Polyclonal Antibody is a Rabbit antibody targeting FGF-23. Anti-FGF-23 Polyclonal Antibody can be used in WB.
别名Fibroblast growth factor 23, FGF-23, Fgf23
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig)
验证活性
1. Sample:
bone (rat) lysate at 40 μg
Primary: Anti-MRPL32 (TMAB-00671) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kDa
Observed band size: 27 kDa
2. Sample:
Lane 1: Bone (Rat) Lysate at 40 μg
Lane 2: Cerebrum (Rat) Lysate at 40 μg
Primary:
Anti-FGF23 (TMAB-00671) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 30/32 kDa
Observed band size: 30 kDa
verifiedActivityverifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Note=Secretion is dependent on O-glycosylation.
组织特异性Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts).
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Fibroblast growth factor 23
抗原种属
Human
基因名称
FGF23
基因ID
8074
蛋白名称
Fibroblast growth factor 23
Uniprot ID
Q9GZV9
功能
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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关键词

Fgf 23
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