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RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
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货号 TMPJ-00349
别名 tumor necrosis factor receptor superfamily member 11A, TRANCER, TRANCE R, TNFRSF11A, receptor activator of nuclear factor-κ B, receptor activator of nuclear factor-kappa B, Receptor activator of NF-KB, RANK1, PDB2, OPTB7, OFE, ODFROSTS, ODFR, FEO, CD265 antigen, CD265
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.
其他形式的 “RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)”:
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPJ-00349 别名 tumor necrosis factor receptor superfamily member 11A, TRANCER, TRANCE R, TNFRSF11A, receptor activator of nuclear factor-κ B, receptor activator of nuclear factor-kappa B, Receptor activator of NF-KB, RANK1, PDB2, OPTB7, OFE, ODFROSTS, ODFR, FEO, CD265 antigen, CD265
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 432 | 6-8日内发货 | |
| 10 μg | ¥ 700 | 6-8日内发货 | |
| 20 μg | ¥ 1,080 | 5日内发货 | |
| 50 μg | ¥ 1,970 | 5日内发货 | |
| 100 μg | ¥ 2,960 | 5日内发货 | |
| 200 μg | ¥ 4,660 | 5日内发货 | |
| 500 μg | ¥ 8,300 | 5日内发货 | |
| 1 mg | ¥ 12,600 | 5日内发货 |
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| 产品描述 | Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas. |
| 生物活性 | Loaded Human RANK-His on HIS1K Biosensor, can bind Human RANK L with an affinity constant of <1 pM as determined in BLI assay. (Regularly tested) |
| 研究背景 | Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-6xHis |
| 蛋白编号 | Q9Y6Q6 |
| 氨基酸序列 | Ile30-Pro212 |
| 蛋白构建 | Ile30-Pro212 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | tumor necrosis factor receptor superfamily member 11A, TRANCER, TRANCE R, TNFRSF11A, receptor activator of nuclear factor-κ B, receptor activator of nuclear factor-kappa B, Receptor activator of NF-KB, RANK1, PDB2, OPTB7, OFE, ODFROSTS, ODFR, FEO, CD265 antigen, CD265 |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 25-30 KDa (reducing condition) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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