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Anti-Keratin 1 Polyclonal Antibody

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货号 TMAB-07983

Anti-Keratin 1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Keratin 1。Anti-Keratin 1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Keratin 1 Polyclonal Antibody

Anti-Keratin 1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07983

Anti-Keratin 1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Keratin 1。Anti-Keratin 1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍


生物活性
产品描述
Anti-Keratin 1 Polyclonal Antibody is a Rabbit antibody targeting Keratin 1. Anti-Keratin 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Note=Located on plasma membrane of neuroblastoma NMB7 cells.
组织特异性The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis. Post-translational modifications : Undergoes deimination of some arginine residues (citrullination).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Keratin 1
抗原种属
Human
基因名称
KRT1
基因ID
蛋白名称
Keratin, type II cytoskeletal 1
Uniprot ID
功能
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinty receptor for kininogen-1/HMWK.
化学信息
分子量Theoretical: 70 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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