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Anti-Keratin 1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Keratin 1。Anti-Keratin 1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-Keratin 1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Keratin 1。Anti-Keratin 1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 |
| 产品描述 | Anti-Keratin 1 Polyclonal Antibody is a Rabbit antibody targeting Keratin 1. Anti-Keratin 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane. Note=Located on plasma membrane of neuroblastoma NMB7 cells. |
| 组织特异性 | The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis. Post-translational modifications : Undergoes deimination of some arginine residues (citrullination). |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]. |
| 免疫原 | KLH conjugated synthetic peptide: human Keratin 1 |
| 抗原种属 | Human |
| 基因名称 | KRT1 |
| 基因ID | |
| 蛋白名称 | Keratin, type II cytoskeletal 1 |
| Uniprot ID | |
| 功能 | May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinty receptor for kininogen-1/HMWK. |
| 分子量 | Theoretical: 70 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |