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顶部生物活性储存和溶解信息计算器

Anti-Phospho-Integrin b3 (Tyr773) Polyclonal Antibody

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产品编号 TMAC-02178

别名 p-Integrin b3 (Y773), p-Integrin b3 (Tyr773), Integrin b3 (p-Y773), Integrin b3 (p-Tyr773)

Anti-Phospho-Integrin b3 (Tyr773) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Integrin b3 (Tyr773)。Anti-Phospho-Integrin b3 (Tyr773) Polyclonal Antibody 可用于 IHC,WB。

Anti-Phospho-Integrin b3 (Tyr773) Polyclonal Antibody

Anti-Phospho-Integrin b3 (Tyr773) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
产品编号 TMAC-02178 别名 p-Integrin b3 (Y773), p-Integrin b3 (Tyr773), Integrin b3 (p-Y773), Integrin b3 (p-Tyr773)

Anti-Phospho-Integrin b3 (Tyr773) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Integrin b3 (Tyr773)。Anti-Phospho-Integrin b3 (Tyr773) Polyclonal Antibody 可用于 IHC,WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Integrin b3 (Tyr773) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Integrin b3 (Tyr773). Anti-Phospho-Integrin b3 (Tyr773) Polyclonal Antibody can be used in IHC,WB.
别名p-Integrin b3 (Y773), p-Integrin b3 (Tyr773), Integrin b3 (p-Y773), Integrin b3 (p-Tyr773)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from 293 cells using Integrin b3 (Phospho-Tyr773) Antibody TMAC-02178 and the same antibody preincubated with blocking peptide.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Integrin b3 (Phospho-Tyr773) Antibody TMAC-02178 (left) or the same antibody preincubated with blocking peptide (right).
verifiedActivityverifiedActivity
应用IHCWB
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Integrin a-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin a-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins a-IIb/beta-3 and a-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin a-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin a-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 773 (P-L-Y(p)-K-E) derived from Human Integrin b3
抗原种属
human
Uniprot ID
P05106
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pIntegrin b3 (Y773)pIntegrin b3 (Tyr773)Integrin b3 (pY773)Integrin b3 (pTyr773)Integrin b3 (phospho-Y773)Integrin b3 (phospho-Tyr773)

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