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TargetMol | Compound Library

抗癌临床化合物库现货

Anti-Cancer Clinical Compound Library
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货号 L2120

尽管在过去的几十年中癌症的研究和治疗取得了巨大的成功，但癌症仍然是人类面临的巨大挑战，给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征，表现出无限的增殖潜能，维持自身生长信号的持续稳定，逃避应激信号(例如治疗药物)诱导的细胞凋亡，刺激血管生长，为肿瘤提供营养，同时逃避免疫系统防御和诱导局部慢性炎症，发挥其侵袭和转移能力，表现出异常的代谢活动，并通过突变和表观遗传机制显著改变全基因组的稳定性。

抗癌活性的药物是临床研究的热点之一，根据文献报道和有关公开资料，我们收集了2760 个具有抗癌活性或潜在抗癌活性的处于临床试验阶段的化合物，组成抗癌临床化合物库，可用于癌症相关研究及高通量高内涵筛选。

TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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货号 L2120

抗癌临床化合物库

规格

  • 1 mg
  • 10 μL x 10 mM (in DMSO)
  • 20 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 2760个具有抗癌活性小分子的独特集合，可用于高通量高内涵筛选；
  • 生物活性已经临床前实验证实，所有化合物均已进入临床实验阶段的抗癌化合物；
  • 包括肺癌、乳腺癌、白血病、淋巴瘤等15种癌症，是癌症相关研究的有效筛选工具；
  • 作用靶点涉及PI3K,HDAC, mTOR, CDK, JAK 等癌症相关靶点；
  • 结构多样，药效显著，可渗透细胞；
  • 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

包装和储存 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
  • 干粉蓝冰运输，DMSO溶液干冰运输；
  • 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
  • 本化合物库通常以 DMSO 10 mM 浓度提供。少量产品可能因溶解性或稳定性需求，采用其他溶剂或浓度包装，具体以实际产品信息为准。

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Apoptosis
Autophagy
Endogenous Metabolite
5-HT Receptor
Antibacterial
Adrenergic Receptor
DNA/RNA Synthesis
Dopamine Receptor
Antibiotic
VEGFR
COX
Potassium Channel
Histamine Receptor
Calcium Channel
EGFR
Parasite
Sodium Channel
PI3K
ROS
CDK
Cytochromes P450
Reactive Oxygen Species
NF-κB
FLT
JAK
PDGFR
Glucocorticoid Receptor
HIV Protease
FGFR
mTOR
c-Kit
Topoisomerase
HDAC
Akt
c-Met/HGFR
PPAR
Microtubule Associated
Ferroptosis
Virus Protease
AChR
SARS-CoV
Prostaglandin Receptor
Src
p38 MAPK
Dehydrogenase
Nucleoside Antimetabolite/Analog
GABA Receptor
Estrogen Receptor/ERR
Antifungal
Mitophagy
ERK
iGluR
Interleukin
Estrogen/progestogen Receptor
Adenosine Receptor
Tyrosine Kinases
Bcr-Abl
Influenza Virus
Caspase
Androgen Receptor
Ras
GPCR
Raf
Epigenetic Reader Domain
TNF
PARP
HSV
P-gp
HSP
Aurora Kinase
Serotonin Transporter
PDE
Bcl-2 Family
ALK
MDM-2/p53
TRP/TRPV Channel
MEK
HER
HBV
Trk receptor
HIF/HIF Prolyl-Hydroxylase
Histone Methyltransferase
RAAS
PKC
Mitochondrial Metabolism
Opioid Receptor
STAT
ATPase
Phosphatase
Wnt/beta-catenin
Norepinephrine
TLR
c-Fms
c-RET
HCV Protease
NMDAR
Endothelin Receptor
AMPK
ROS Kinase
JNK
E1/E2/E3 Enzyme
MMP
Beta Amyloid
DNA Alkylator/Crosslinker
GSK-3
Drug Metabolite
Chk
TAM Receptor
FAK
Proton pump
LPL Receptor
Progesterone Receptor
Gamma-secretase
Molecular Glues
Retinoid Receptor
S1P Receptor
Kras
Guanylate cyclase
CXCR
GluR
IGF-1R
TGF-beta/Smad
SGLT
Reverse Transcriptase
HIF
CFTR
NO Synthase
Carbonic Anhydrase
DNA-PK
Antifolate
IL Receptor
Nrf2
p53
Proteasome
Antioxidant
PKA
ROCK
P2X Receptor
DNA Alkylation
ATM/ATR
Syk
S6 Kinase
Transferase
ADC Cytotoxin
GNRH Receptor
IAP
Hedgehog/Smoothened
Vasopressin Receptor
PLK
HMG-CoA Reductase
Mdm2
DHFR
Integrin
P2Y Receptor
MAO
IDO
CSF-1R
Isocitrate Dehydrogenase (IDH)
Ligands for E3 Ligase
Angiotensin-converting Enzyme (ACE)
Lipoxygenase
Indoleamine 2,3-Dioxygenase (IDO)
MAPK
Anti-infection
Kinesin
Monoamine Oxidase
BTK
Histone Demethylase
Glutathione Peroxidase
MRP
Serine Protease
Leukotriene Receptor
Antifection
PAK
OX Receptor
Sirtuin
Casein Kinase
IκB/IKK
Cannabinoid Receptor
DNA Methyltransferase
IRAK
RIP kinase
Smo
DNA
Antiviral
Phospholipase
Hydroxylase
Sigma receptor
PROTACs
Reductase
Tie-2
Pim
FXR
Glucagon Receptor
CCR
Bradykinin Receptor
Ephrin Receptor
Neurokinin receptor
PD-1/PD-L1
IKZF
IFNAR
PERK
Serine/threonin kinase
PYK2
DPP-4
Cholinesterase (ChE)
Xanthine Oxidase
Telomerase
STING
GPCR19
CRFR
RSV
GHSR
NOD
Tyrosinase
Thrombin
NOD-like Receptor (NLR)
Chloride channel
CRM1
YAP
NADPH
Melatonin Receptor
Cholecystokinin Receptor
Photosensitizer
NAMPT
Glutaminase
Aryl Hydrocarbon Receptor
ABC Transporter
Na-K-Cl cotransporter
Glucosidase
Monoamine Transporter
Fatty Acid Synthase
Neuropeptide Y Receptor
Somatostatin
glycosidase
CaMK
DUB
Wee1
PGE Synthase
GST
Aromatase
Oxytocin Receptor
CGRP Receptor
AhR
ROR
LTR
c-Myc
CaSR
Rho
IRE1
Annexin A
MT Receptor
KSP
ATP Citrate Lyase
BCRP
OXPHOS
Beta-Secretase
OAT
Survivin
Free radical scavengers
Aminopeptidase
transporter
Decarboxylase
FKBP
ribosome
Melanocortin Receptor
Adenosine Deaminase
Cuproptosis
Discoidin Domain Receptor (DDR)
Gap Junction Protein
Protease-activated Receptor
MLK
NOS
Monocarboxylate transporter
NEDD8
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
Arginase
DYRK
Necroptosis
TOPK
VDA
Galectin
Cysteine Protease
RANKL/RANK
UGT
LDL
GRK
DNA gyrase
Hexokinase
PROTAC Linker
HCN Channel
Thrombopoietin Receptor
Huntingtin
Acyltransferase
Porcupine
CD73
Histone Acetyltransferase
PAI-1
LPA Receptor
PI4K
PDK
SGK
Complement System
p97
PGC-1α
Thyroid hormone receptor(THR)
Advanced Glycation End Products
MicroRNA
NPC1L1
Hydrogenase
RAR/RXR
MALT
MyD88
Factor VIIa
Cell wall
MIF
GTPase
Factor Xa
OCT
Kisspeptin
N-Acetylglucosaminyltransferase
Hck
ATG
Cell Cycle Arrest
Liver X Receptor
Neurotensin Receptor
LIM Kinase
Glucokinase
Stemness kinase
Myosin
Adenylate cyclase
PAFR
MTH1
GlyT
Anion Exchanger
Thioredoxin
ACK1
HCAR
Cadherin
Lipid
PSMA
MNK
E3 Ligase Ligand-Linker Conjugates
ASK
GluCls
Pyroptosis
MELK
Methionine Adenosyltransferase (MAT)
Neprilysin
Hippo pathway
KLF
Aquaporin
FOXO
RXFP receptor
NADPH-oxidase
BMI-1
Liposome
Imidazoline Receptor
Ferroportin
Vitamin
Drug-Linker Conjugates for ADC

Keywords

AntiCancer Clinical Compound LibraryAnti Cancer Clinical Compound Library