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顶部生物活性储存和溶解信息计算器

Anti-ULK1 Antibody (6P282)

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Anti-ULK1 Antibody (6P282)
产品编号 TMAC-04195
别名 Unc-51-like kinase 1, Unc-51 like kinase 1(C. elegans), UNC51, Unc 51(C. elegans) like kinase 1, Unc 51 like kinase 1, UNC 51, ULK1, ULK 1, Serine/threonine protein kinase Unc51.1, Serine/threonine protein kinase ULK1, hATG1, Autophagy-related protein 1 homolog, ATG1A, ATG1, ATG 1

Anti-ULK1 Antibody (6P282) 是一种 Rabbit 抗体，靶向 ULK1。Anti-ULK1 Antibody (6P282) 可用于 WB,IHC。

Anti-ULK1 Antibody (6P282)

Anti-ULK1 Antibody (6P282)

Rating icon 还可以
Anti-ULK1 Antibody (6P282)
产品编号 TMAC-04195 别名 Unc-51-like kinase 1, Unc-51 like kinase 1(C. elegans), UNC51, Unc 51(C. elegans) like kinase 1, Unc 51 like kinase 1, UNC 51, ULK1, ULK 1, Serine/threonine protein kinase Unc51.1, Serine/threonine protein kinase ULK1, hATG1, Autophagy-related protein 1 homolog, ATG1A, ATG1, ATG 1

Anti-ULK1 Antibody (6P282) 是一种 Rabbit 抗体，靶向 ULK1。Anti-ULK1 Antibody (6P282) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-ULK1 Antibody (6P282) is a Rabbit antibody targeting ULK1. Anti-ULK1 Antibody (6P282) can be used in WB,IHC.
别名Unc-51-like kinase 1, Unc-51 like kinase 1(C. elegans), UNC51, Unc 51(C. elegans) like kinase 1, Unc 51 like kinase 1, UNC 51, ULK1, ULK 1, Serine/threonine protein kinase Unc51.1, Serine/threonine protein kinase ULK1, hATG1, Autophagy-related protein 1 homolog, ATG1A, ATG1, ATG 1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of ULK1 on different cell lysate using anti-ULK1 antibody at 1/1,000 dilution. Positive control: Lane1: MCF-7, Lane2: Mouse spleen, Lane3: SH-SY5Y.
2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-ULK1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded rat skeleton muscle tissue using anti-ULK1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-ULK1 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-ULK1 antibody. Counter stained with hematoxylin.
应用
WB
IHC
推荐剂量
WB: 1:500-2000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. May also phosphorylate SESN2 and SQSTM1 to regulate autophagy.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
O75385
化学信息
分子量Theoretical: 112 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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