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Anti-MYST1/KAT8 Polyclonal Antibody 2

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货号 TMAB-09193

Anti-MYST1/KAT8 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 MYST1/KAT8。Anti-MYST1/KAT8 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-MYST1/KAT8 Polyclonal Antibody 2

Anti-MYST1/KAT8 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-09193

Anti-MYST1/KAT8 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 MYST1/KAT8。Anti-MYST1/KAT8 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,965
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200 μL
¥ 2,780
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产品介绍


生物活性
产品描述
Anti-MYST1/KAT8 Polyclonal Antibody 2 is a Rabbit antibody targeting MYST1/KAT8. Anti-MYST1/KAT8 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Chromosome.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Dosage compensation ensures that males with a single X chromosome and females with two X chromosomes have the same amount of most X-linked gene products. In Drosophila, this is acheived by enhancing the level of transcription of the X chromosome in males. Proteins such as maleless, male specific lethal 1, 2 and 3, and males absent on the first (MOF) form a dosage compensation complex (DCC) that is required for the twofold increase of transcription of the male X chromosome. The DCC is preferentially associated with many sites on the X chromosome in somatic cells of males. The binding of the DCC to the X chromosome is dependent upon histone 4 acetylation at lysine 16, which is accomplished by MOF. In mammals, MOF (also designated hMOF, MYST1, or MOZ) belongs to the MYST family of histone acetyl transferases which are characterized by a unique C2HC-type zinc finger close to their HAT domains. MOF utilizes the zinc finger domain to contact the globular part of the nucleosome as well as the histone H4 N-terminal tail substrate. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone acetyltransferases.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MOF/KAT8/MYST1
抗原种属
Human
基因名称
KAT8
基因ID
蛋白名称
Histone acetyltransferase KAT8
Uniprot ID
功能
Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM.
化学信息
分子量Theoretical: 52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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