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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD40L Polyclonal Antibody

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货号 TMAB-03984

Anti-CD40L Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD40L。Anti-CD40L Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-CD40L Polyclonal Antibody

Anti-CD40L Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03984

Anti-CD40L Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD40L。Anti-CD40L Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD40L Polyclonal Antibody is a Rabbit antibody targeting CD40L. Anti-CD40L Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted and Cell membrane.
组织特异性Specifically expressed on activated CD4+ T-lymphocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD40L
抗原种属
Human
基因名称
CD40LG
基因ID
959
蛋白名称
CD40 ligand
Uniprot ID
P29965
功能
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching.
Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
化学信息
分子量Theoretical: 29 kDa. Actual: 32-39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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