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Anti-MSH6 Antibody (5V942) 是一种 Mouse 抗体,靶向 MSH6。Anti-MSH6 Antibody (5V942) 可用于 ELISA, IHC。
Anti-MSH6 Antibody (5V942) 是一种 Mouse 抗体,靶向 MSH6。Anti-MSH6 Antibody (5V942) 可用于 ELISA, IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μg | ¥ 1,305 | 5日内发货 | |
100 μg | ¥ 2,190 | 5日内发货 |
产品描述 | Anti-MSH6 Antibody (5V942) is a Mouse antibody targeting MSH6. Anti-MSH6 Antibody (5V942) can be used in ELISA, IHC. |
别名 | Sperm associated protein, p160, MutS-alpha 160 kDa subunit, mutS homolog 6, MutS alpha 160 kDa subunit, mutS (E. coli) homolog 6, MSH 6, HSAP, HNPCC5, HNPCC 5, hMSH6, GTMBP, GTBP, G/T mismatch binding protein, DNA mismatch repair protein Msh6 |
Ig Type | IgG |
克隆号 | 5V942 |
交叉反应 | Human |
验证活性 | Immunohistochemical of paraffin-embedded Human lung cancer tissue using TMAH-00785 at dilution of 1:200. |
应用 | ELISA, IHC |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
亚细胞定位 | Nucleus. Chromosome. Note=Associates with H3K36me3 via its PWWP domain. |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Protein G purified |
性状 | Liquid |
缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
纯度 | >95% |
研究背景 | Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding a... |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: Human MSH6 Protein |
抗原种属 | Human |
基因ID | 2956 |
Uniprot ID | |
研究领域 | Epigenetics and Nuclear Signaling |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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