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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Nectin 3 Polyclonal Antibody

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货号 TMAB-09331

Anti-Nectin 3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Nectin 3。Anti-Nectin 3 Polyclonal Antibody 可用于 WB。

Anti-Nectin 3 Polyclonal Antibody

Anti-Nectin 3 Polyclonal Antibody

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货号 TMAB-09331

Anti-Nectin 3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Nectin 3。Anti-Nectin 3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Nectin 3 Polyclonal Antibody is a Rabbit antibody targeting Nectin 3. Anti-Nectin 3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Cow,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass membrane protein (Potential).
组织特异性Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Nectins are immunoglobulin-like adhesion molecules that interact with afadin. Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin-catenin system in epithelial cells. The nectin/PRR-family consists of four members, nectin-1, -2, -3 and -4. All the members of the nectin family have two or three slice variants. Nectin 3 is mainly expressed in testis and placental tissues and interacts in vivo with both long and short isoforms of afadin.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Nectin 3
抗原种属
Human
基因名称
NECTIN3
基因ID
25945
蛋白名称
Nectin-3
Uniprot ID
Q9NQS3
功能
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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