Name: Kremen-1 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-01144
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 418

6-8日内发货

10 μg

¥ 676

6-8日内发货

20 μg

¥ 1,090

5日内发货

50 μg

¥ 2,190

5日内发货

100 μg

¥ 3,700

5日内发货

200 μg

¥ 6,690

5日内发货

500 μg

¥ 14,800

5日内发货

生物活性

产品描述	KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds to the mature viral particle above the canyon of the viral protein 1 (VP1) subunit and contacts across two adjacent asymmetry units. The key residues for receptor binding are conserved among most KRM1-dependent enteroviruses, suggesting a uniform mechanism for receptor binding.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds to the mature viral particle above the canyon of the viral protein 1 (VP1) subunit and contacts across two adjacent asymmetry units. The key residues for receptor binding are conserved among most KRM1-dependent enteroviruses, suggesting a uniform mechanism for receptor binding.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q96MU8-1
蛋白构建	Arg21-Thr392
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	KRM1, KREMEN1, Kremen protein 1, KREMEN
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	67.6 kDa (predicted). Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Kremen-1 Protein, Human, Recombinant (hFc)

Kremen-1 Protein, Human, Recombinant (hFc)

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