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Anti-TCPTP Antibody (6E858)
还可以产品编号 TMAY-03465
Anti-TCPTP Antibody (6E858) 是一种 Rabbit 抗体，靶向 TCPTP。Anti-TCPTP Antibody (6E858) 可用于 ELISA。
Anti-TCPTP Antibody (6E858)
Anti-TCPTP Antibody (6E858)
还可以产品编号 TMAY-03465
Anti-TCPTP Antibody (6E858) 是一种 Rabbit 抗体，靶向 TCPTP。Anti-TCPTP Antibody (6E858) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-TCPTP Antibody (6E858) is a Rabbit antibody targeting TCPTP. Anti-TCPTP Antibody (6E858) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6E858 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PTPN2 / TC-PTP (rM PTPN2 / TC-PTP; TMPY-02369; Q06180-1; Ser2-Asn314). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Tyrosine-protein phosphatase non-receptor type 2, also known as T-cell protein-tyrosine phosphatase, PTPN2 and PTPT, is a cytoplasm protein that belongs to the protein-tyrosine phosphatase family and Non-receptor class 1 subfamily. Members of the protein tyrosine phosphatase ( PTP ) family share a highly conserved catalytic motif, which is essential for the catalytic activity. TC-PTP / PTPN2 is a cytosolic tyrosine phosphatase that functions as a negative regulator of a variety of tyrosine kinases and other signaling proteins. The expression of TC-PTP / PTPN2 plays a role of tumor suppressor and may modulate response to treatment. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. TC-PTP / PTPN2 is an enzyme that is essential for the proper functioning of the immune system and that participates in the control of cell proliferation, and inflammation. TC-PTP / PTPN2 was identified as a negative regulator of NUP214-ABL1 kinase activity. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse PTPN2 / TC-PTP Protein (TMPY-02369) |
| 抗原种属 | Mouse |
| 研究领域 | Phosphatases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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