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顶部生物活性储存和溶解信息计算器

Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516)

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产品编号 TMAY-01576

别名 S6 Ribosomal Protein (p-Ser240, 244), S6 Ribosomal Protein (p-S240, 244), S6, p-S6 Ribosomal Protein (Ser240, 244), p-S6 Ribosomal Protein (S240, 244), Phospho-S6 Ribosomal Protein (S240, 244), OK/SW-cl.2, eS6

Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) 是一种 Rabbit 抗体，靶向 Phospho-S6 Ribosomal Protein (Ser240, 244)。Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) 可用于 IHC-P,WB。

Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516)

Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516)

一键复制产品信息
Rating icon 还可以
产品编号 TMAY-01576 别名 S6 Ribosomal Protein (p-Ser240, 244), S6 Ribosomal Protein (p-S240, 244), S6, p-S6 Ribosomal Protein (Ser240, 244), p-S6 Ribosomal Protein (S240, 244), Phospho-S6 Ribosomal Protein (S240, 244), OK/SW-cl.2, eS6

Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) 是一种 Rabbit 抗体，靶向 Phospho-S6 Ribosomal Protein (Ser240, 244)。Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) 可用于 IHC-P,WB。

规格价格库存数量
20 μL
¥ 694
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100 μL
¥ 1,984
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产品介绍

生物活性
产品描述
Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) is a Rabbit antibody targeting Phospho-S6 Ribosomal Protein (Ser240, 244). Anti-Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody (9Q516) can be used in IHC-P,WB.
别名S6 Ribosomal Protein (p-Ser240, 244), S6 Ribosomal Protein (p-S240, 244), S6, p-S6 Ribosomal Protein (Ser240, 244), p-S6 Ribosomal Protein (S240, 244), Phospho-S6 Ribosomal Protein (S240, 244), OK/SW-cl.2, eS6
Ig Type
Rabbit IgG
克隆号
9Q516
交叉反应
Human;
Species predicted to react based on 100% sequence homology: Mouse
特异性
Human
Species predicted to react based on 100% sequence homology: Mouse
验证活性
1. Western blot analysis of extracts from serum-starved HEK293, untreated (-) or treated with 20% FBS, using Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody, Rabbit MAb (upper), or Anti-RPS6 Antibody, Rabbit Polyclonal (lower) at 1:1000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human carcinoma of sigmoid tissue,untreated (left) or lambda phosphatase-treated (right), using Recombinant Phospho-S6 Ribosomal Protein (Ser240/244) Antibody, Rabbit Monoclonal at 1:2000 dilution.
3. Western blot analysis of extracts from serum-starved HEK293, treated with 20% FBS (30 min), using Phospho-S6 Ribosomal Protein (Ser240, 244) Antibody, Rabbit MAb at dilution of 1:1000, 1:5000 and 1:25000. (Validation Experiment)
4. Western blot analysis of extracts from serum-starved HEK293, untreated (line A); treated with FBS(20%, 30min) (line B); treated with FBS and λ-phosphatase (line C) using Phospho-S6 Ribosomal Protein (Ser240, 244) rabbit monoclonal Antibody at 1:5000 dilution. (Validation Experiment)
5. Western blot analysis of extracts from serum-starved , untreated (line A); treated with FBS(20%, 30min), without peptide (line B) or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-S6 Ribosomal Protein (Ser240, 244) rabbit monoclonal Antibody at 1:5000 dilution. (Validation Experiment)
应用IHC-PWB
推荐剂量
WB: 1:1000-1:5000; IHC-P: 1:1000-1:5000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式The antibody is produced by immunizing rabbits with a synthetic phosphopeptide corresponding to residues around (Ser240, 244) of Human Phospho-S6 Ribosomal Protein.
纯化方式Protein A
性状Liquid
缓冲液10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
研究背景Ribosomal protein S6 (rpS6), a component of the 40S ribosomal subunit, is involved in multiple cellular bioactivities. RPS6 is a downstream substrate of PI3K/Akt/mTOR/ kinase and MAPK kinase pathways and its dephosphorylation is also triggered by DNA double-strand breaks. The ribosomal protein S6 (RPS6) is a downstream component of the signaling mediated by the target of rapamycin (TOR) kinase that acts as a central regulator of the key metabolic processes, such as protein translation and ribosome biogenesis, in response to various environmental cues. mTORC1/rpS6 signaling complex promoted Sertoli blood-testis barrier (BTB) remodeling by perturbing Sertoli cell-cell adhesion site known as the basal ectoplasmic specialization (ES). mTORC1/rpS6 complex also promoted disruption of spermatid adhesion at the Sertoli-spermatid interface called the apical ES.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide corresponding to residues around (Ser240, 244) of Human Phospho-S6 Ribosomal Protein.
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

S6 Ribosomal Protein (pSer240, 244)S6 Ribosomal Protein (pS240, 244)S6 Ribosomal Protein (phospho-Ser240, 244)S6 Ribosomal Protein (phospho-S240, 244)pS6 Ribosomal Protein (Ser240, 244)pS6 Ribosomal Protein (S240, 244)

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