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Anti-UCHL3 Antibody (8N907) 是一种 Rabbit 抗体,靶向 UCHL3。Anti-UCHL3 Antibody (8N907) 可用于 ELISA。
Anti-UCHL3 Antibody (8N907) 是一种 Rabbit 抗体,靶向 UCHL3。Anti-UCHL3 Antibody (8N907) 可用于 ELISA。
产品描述 | Anti-UCHL3 Antibody (8N907) is a Rabbit antibody targeting UCHL3. Anti-UCHL3 Antibody (8N907) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8N907 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human UCHL3 (rh UCHL3; TMPY-01548; NP_005993.1; Glu 2-Ala 230). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Ubiquitin carboxyl-terminal hydrolase isozyme L3, also known as UCH-L3, Ubiquitin thioesterase L3 and UCHL3, is a ubiquitin-protein hydrolase that belongs to the peptidase C12 family. It is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. UCHL3 is highly expressed in heart, skeletal muscle, and testis. UCHL1 and UCHL3 are two of the deubiquitinating enzymes expressed in the brain. These phenotypes indicate the importance of UCHL1 and UCHL3 in the regulation of the central nervous system. UCHL3 functions as a de-ubiquitinating enzyme where lack of its hydrolase activity may result in the prominent accumulation of ubiquitinated proteins and subsequent induction of stress responses in skeletal muscle. UCHL3 has also been identified as a tumor-specific antigen in colon cancer. |
偶联 | Unconjugated |
免疫原 | Recombinant Human UCHL3 Protein (TMPY-01548) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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