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Anti-SEC31A Antibody (5Y312) 是一种 Mouse 抗体,靶向 SEC31A。Anti-SEC31A Antibody (5Y312) 可用于 WB,IHC。
Anti-SEC31A Antibody (5Y312) 是一种 Mouse 抗体,靶向 SEC31A。Anti-SEC31A Antibody (5Y312) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,980 | 5日内发货 | |
100 μL | ¥ 2,980 | 5日内发货 |
产品描述 | Anti-SEC31A Antibody (5Y312) is a Mouse antibody targeting SEC31A. Anti-SEC31A Antibody (5Y312) can be used in WB,IHC. |
别名 | Yeast Sec31p homolog, Web1 like protein, VAP1, SEC31L1, SEC31 related protein A, SEC31 like protein 1, SEC31 like 1, SEC31 homolog A (S. cerevisiae), SEC 31A, Protein transport protein Sec31A, MGC93320, MGC90305, KIAA0905, HSPC334, HSPC275, DKFZp686N07171, AU042160, ABP130, ABP125, 1810024J13Rik |
克隆号 | 5Y312 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of SEC31A on human SEC31A recombinant protein using anti-SEC31A antibody at 1/1,000 dilution. 2. Western blot analysis of SEC31A on HEK293 (1) and SEC31A-hIgGFc transfected HEK293 (2) cell lysate using anti-SEC31A antibody at 1/1,000 dilution. 3. Immunohistochemical analysis of paraffin-embedded human ?ovarian cancer tissue using anti-SEC31A antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. Sec31A, also known as ABP125, ABP130 or SEC31L1, is a 1,220 amino acid protein that contains seven WD repeats and localizes to the cytoplasm and to cytoplasmic vesicles, as well as to the membrane of the endoplasmic reticulum (ER). Expressed ubiquitously at high levels, Sec31A functions as a component of the COP II (coat protein II) complex and, working in tandem with other proteins, promotes the formation of ER transport vesicles and aids in the selection of cargo molecules. Chromosomal aberrations that involve the Sec31A gene are associated with inflammatory myofibroblastic tumors (IMTs), suggesting a role for Sec31A in carcinogenesis. Multiple isoforms of Sec31A exist due to alternative splicing events. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 133 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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