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Anti-Phospho-RPS6KA5 (Ser212) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-RPS6KA5 (Ser212)。Anti-Phospho-RPS6KA5 (Ser212) Polyclonal Antibody 可用于 WB。
Anti-Phospho-RPS6KA5 (Ser212) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-RPS6KA5 (Ser212)。Anti-Phospho-RPS6KA5 (Ser212) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-RPS6KA5 (Ser212) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA5 (Ser212). Anti-Phospho-RPS6KA5 (Ser212) Polyclonal Antibody can be used in WB. |
别名 | S6K-alpha-5, S6K alpha 5, RSK-like protein kinase, RSKL, RSK Like Protein Kinase, RPS6KA5 (p-Ser212), RPS6KA5 (p-S212), RLPK, Ribosomal protein S6 kinase alpha-5, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase 90kD polypeptide 5, p-RPS6KA5 (Ser212), p-RPS6KA5 (S212), Phospho-RPS6KA5 (S212), Nuclear Mitogen And Stress Activated Protein Kinase 1, MSPK1, Mitogen and stress activated protein kinase 1, MGC1911, KS6A5_HUMAN, EC 2.7.11.1, 90 kDa ribosomal protein S6 kinase 5 |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of extracts from NIH-3T3 cells treated with EGF using MSK1 (Phospho-Ser212) antibody TMAC-02654. The lane on the right is treated with the antigen-specific peptide. |
应用 | |
推荐剂量 | WB: 1:500-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14). |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 212 (A-Y-S(p)-F-C) derived from Human MSK1 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 90 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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