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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-AMBRA1 Polyclonal Antibody

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货号 TMAB-02506

Anti-AMBRA1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AMBRA1。Anti-AMBRA1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-AMBRA1 Polyclonal Antibody

Anti-AMBRA1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02506

Anti-AMBRA1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AMBRA1。Anti-AMBRA1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-AMBRA1 Polyclonal Antibody is a Rabbit antibody targeting AMBRA1. Anti-AMBRA1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic vesicle, autophagosome.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景AMBRA1 regulates autophagy and development of the nervous system. It is a large, previously unknown protein bearing a WD40 domain at its amino terminus, regulates autophagy and has a crucial role in embryogenesis. AMBRA1 is a positive regulator of the Becn1-dependent programme of autophagy, as revealed by its overexpression and by RNA interference experiments invitro. Notably, AMBRA1 functional deficiency in mouse embryos leads to severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic cell death.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AMBRA1
抗原种属
Human
基因名称
AMBRA1
基因ID
55626
蛋白名称
Activating molecule in BECN1-regulated autophagy protein 1
Uniprot ID
Q9C0C7
功能
Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
化学信息
分子量Theoretical: 143 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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