SCF Protein, Mouse, Recombinant

Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.

规格	价格/CNY		数量
10 μg	￥ 870	现货
50 μg	￥ 1,960	5日内发货
500 μg	￥ 8,880	5日内发货
1 mg	￥ 13,900	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 870

现货

50 μg

￥ 1,960

5日内发货

500 μg

￥ 8,880

5日内发货

1 mg

￥ 13,900

5日内发货

生物活性

Measured by the dose-dependent stimulation of TF-1 cells. The ED50 for this effect is 4-12 ng/ml. (QC verified)

TargetMol Bioactive

产品描述

种属	Mouse
表达系统	E. coli
标签	Tag Free
蛋白编号	P20826
别名	SCF, Hematopoietic growth factor KL, MGF, Steel factor, Mast cell growth factor, Stem cell factor, Kit ligand
氨基酸序列	Lys26-Ala189
蛋白构建	Lys26-Ala189
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	16 KDa (reducing condition)

内毒素	< 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.

计算器

复溶计算器

重组蛋白稀释计算器

比活力计算器

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

bottom

SCF Protein, Mouse, Recombinant

计算器

技术支持

Keywords