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顶部生物活性储存和溶解信息计算器

Anti-PTEN Antibody (9S478)

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Anti-PTEN Antibody (9S478)
产品编号 TMAC-03460
别名 TEP1, PTEN1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin like protein, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1, MHAM, MGC11227, GLM2, DEC, BZS, 10q23del

Anti-PTEN Antibody (9S478) 是一种 Rabbit 抗体，靶向 PTEN。Anti-PTEN Antibody (9S478) 可用于 WB,ICC/IF,IHC。

Anti-PTEN Antibody (9S478)

Anti-PTEN Antibody (9S478)

Rating icon 还可以
Anti-PTEN Antibody (9S478)
产品编号 TMAC-03460 别名 TEP1, PTEN1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin like protein, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1, MHAM, MGC11227, GLM2, DEC, BZS, 10q23del

Anti-PTEN Antibody (9S478) 是一种 Rabbit 抗体，靶向 PTEN。Anti-PTEN Antibody (9S478) 可用于 WB,ICC/IF,IHC。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-PTEN Antibody (9S478) is a Rabbit antibody targeting PTEN. Anti-PTEN Antibody (9S478) can be used in WB,ICC/IF,IHC.
别名TEP1, PTEN1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin like protein, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1, MHAM, MGC11227, GLM2, DEC, BZS, 10q23del
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PTEN on different lysates using anti-PTEN antibody at 1/1,000 dilution. Positive control: Lane 1: MCF-7, Lane 2: Hela, Lane 3: 293T.
2. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-PTEN antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-PTEN antibody. Counter stained with hematoxylin.
4. ICC staining PTEN in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining PTEN in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining PTEN in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景As human tumors progress to advanced stages, one genetic alteration that occurs at high frequency is a loss of heterozygosity (LOH) at chromosome 10q23. Mapping of homozygous deletions on this chromosome led to the isolation of the PTEN gene, also designated MMAC1 (for mutated in multiple advanced cancers) and TEP1. This candidate tumor suppressor gene exhibits a high frequency of mutations in human glioblastomas and is also mutated in other cancers, including sporadic brain, breast, kidney and prostate cancers. PTEN has been associated with Cowden disease, an autosomal dominant cancer predisposition syndrome. The PTEN gene product is a putative protein tyrosine phosphatase that is localized to the cytoplasm and shares extensive homology with the cytoskeletal proteins tensin and auxilin. Gene transfer studies have indicated that the phosphatase domain of PTEN is essential for growth suppression of glioma cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P60484
化学信息
分子量Theoretical: 54 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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