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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CATSPER2 Polyclonal Antibody

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货号 TMAB-03697

Anti-CATSPER2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CATSPER2。Anti-CATSPER2 Polyclonal Antibody 可用于 WB。

Anti-CATSPER2 Polyclonal Antibody

Anti-CATSPER2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03697

Anti-CATSPER2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CATSPER2。Anti-CATSPER2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CATSPER2 Polyclonal Antibody is a Rabbit antibody targeting CATSPER2. Anti-CATSPER2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specifically located in the principal piece of sperm tail.
组织特异性Testis-specific.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. This gene is part of a tandem repeat on chromosome 15q15; the second copy of this gene is thought to be a pseudogene. Additional splice variants have been described but their full-length nature has not been determined. [provided by RefSeq, Aug 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human CATSPER2
抗原种属
Human
基因名称
CATSPER2
基因ID
117155
蛋白名称
Cation channel sperm-associated protein 2
Uniprot ID
Q8NHT9
功能
Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH.
化学信息
分子量Theoretical: 58 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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