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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NR5A2 Antibody (5J673)

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货号 TMAB-09625

Anti-NR5A2 Antibody (5J673) 是一种 Rabbit 抗体，靶向 NR5A2。Anti-NR5A2 Antibody (5J673) 可用于 WB。

Anti-NR5A2 Antibody (5J673)

Anti-NR5A2 Antibody (5J673)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09625

Anti-NR5A2 Antibody (5J673) 是一种 Rabbit 抗体，靶向 NR5A2。Anti-NR5A2 Antibody (5J673) 可用于 WB。

规格价格库存数量
25 μL
¥ 780
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50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-NR5A2 Antibody (5J673) is a Rabbit antibody targeting NR5A2. Anti-NR5A2 Antibody (5J673) can be used in WB.
Ig Type
IgG
克隆号
5J673
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in hepG2. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and hepG2 cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex.
抗原信息
免疫原
A synthesized peptide: human NR5A2
抗原种属
Human
基因名称
NR5A2
基因ID
2494
蛋白名称
Nuclear receptor subfamily 5 group A member 2
Uniprot ID
O00482
功能
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
化学信息
分子量Theoretical: 61 kDa. Actual: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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