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Anti-NR5A2 Antibody (5J673)

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货号 TMAB-09625

Anti-NR5A2 Antibody (5J673) 是一种 Rabbit 抗体，靶向 NR5A2。Anti-NR5A2 Antibody (5J673) 可用于 WB。

Anti-NR5A2 Antibody (5J673)

Anti-NR5A2 Antibody (5J673)

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Rating icon 还可以
货号 TMAB-09625

Anti-NR5A2 Antibody (5J673) 是一种 Rabbit 抗体，靶向 NR5A2。Anti-NR5A2 Antibody (5J673) 可用于 WB。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-NR5A2 Antibody (5J673) is a Rabbit antibody targeting NR5A2. Anti-NR5A2 Antibody (5J673) can be used in WB.
Ig Type
IgG
克隆号
5J673
反应种属
Human,Mouse,Rat
验证活性
25 μg total protein per lane of various lysates (see on figure) probed with NR5A2 monoclonal antibody, unconjugated (TMAB-09625) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in hepG2. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and hepG2 cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex.
抗原信息
免疫原
A synthesized peptide: human NR5A2
抗原种属
Human
基因名称
NR5A2
基因ID
2494
蛋白名称
Nuclear receptor subfamily 5 group A member 2
Uniprot ID
O00482
功能
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
化学信息
分子量Theoretical: 61 kDa. Actual: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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