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Anti-CD79A Antibody (9P139)

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Anti-CD79A Antibody (9P139)
产品编号 TMAH-00221
别名 MB-1, IGA, CD79a molecule, immunoglobulin-associated α, CD79a molecule, immunoglobulin-associated alpha

Anti-CD79A Antibody (9P139) 是一种抗体,靶向 CD79A。Anti-CD79A Antibody (9P139) 可用于 ELISA。

Anti-CD79A Antibody (9P139)

Anti-CD79A Antibody (9P139)

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Anti-CD79A Antibody (9P139)
产品编号 TMAH-00221 别名 MB-1, IGA, CD79a molecule, immunoglobulin-associated α, CD79a molecule, immunoglobulin-associated alpha

Anti-CD79A Antibody (9P139) 是一种抗体,靶向 CD79A。Anti-CD79A Antibody (9P139) 可用于 ELISA。

规格价格库存数量
50 μL
¥ 1,300
5日内发货
100 μL
¥ 2,180
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD79A Antibody (9P139) is an antibody targeting CD79A. Anti-CD79A Antibody (9P139) can be used in ELISA.
别名MB-1, IGA, CD79a molecule, immunoglobulin-associated α, CD79a molecule, immunoglobulin-associated alpha
Ig Type
hIgG1
克隆号
9P139
交叉反应
Human
验证活性
1. The Binding Activity of Human CD79A with Anti-CD79A recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD79A at 2 μg/mL can bind Anti-CD79A recombinant antibody. The EC50 is 1.521-1.700 ng/mL.
2. The Binding Activity of Human CD79A&CD79B with Anti-CD79A recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD79A&CD79B at 2 μg/mL can bind Anti-CD79A recombinant antibody. The EC50 is 8.012-9.339 ng/mL.
3. The purity of CD79A was greater than 95% as determined by SEC-HPLC
4. The Binding Activity of Human CD79A with Anti-CD79A recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD79A at 2 μg/mL can bind Anti-CD79A recombinant antibody. The EC50 is 14.44-16.80 ng/mL.
5. Untransfected HEK-293T cells (green line) and transfected Human CD79A&CD79B HEK-293T stable cells (red line) were stained with anti-CD79A antibody(TMAH-00221) (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
6. Untransfected HEK-293T cells (green line) and transfected Human CD79A HEK-293T pool cells (red line) were stained with anti-CD79A antibody(TMAH-00221) (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
应用
ELISA
推荐剂量
ELISA:1:5000-1:50000.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Single-pass type I membrane protein.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CD79A Protein
抗原种属
Human
基因ID
973
Uniprot ID
研究领域
Immunology
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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