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Anti-Oncostatin M/OSM Antibody (8Z261)
还可以产品编号 TMAY-00848
Anti-Oncostatin M/OSM Antibody (8Z261) 是一种 Mouse 抗体，靶向 Oncostatin M/OSM。Anti-Oncostatin M/OSM Antibody (8Z261) 可用于 ELISA。
Anti-Oncostatin M/OSM Antibody (8Z261)
Anti-Oncostatin M/OSM Antibody (8Z261)
还可以产品编号 TMAY-00848
Anti-Oncostatin M/OSM Antibody (8Z261) 是一种 Mouse 抗体，靶向 Oncostatin M/OSM。Anti-Oncostatin M/OSM Antibody (8Z261) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Oncostatin M/OSM Antibody (8Z261) is a Mouse antibody targeting Oncostatin M/OSM. Anti-Oncostatin M/OSM Antibody (8Z261) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8Z261 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Oncostatin M / OSM (rh Oncostatin M / OSM; TMPY-02364; P13725; Met1-Arg221). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth. Oncostatin M (OSM) is considered as a pleiotropic cytokine that signals through cell surface receptors typeⅠand typeⅡ both of which share the similarity of containing protein gp130 and takes part in many bio metabolism processes including liver development, hematopoiesis, inflammation, bone formation, and destruction and possibly CNS development. Oncostatin M (OSM) was previously identified by its ability to inhibit the growth of cells from melanoma and other solid tumors. It also has been reported that OSM, like LIF, IL-6, and G-CSF, can inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells. The human form of OSM is insensitive between pH2 and 11 and resistant to heating for one hour at 56 degrees but is not stable at 90 degrees. The human OSM is produced as a precursor containing 252 amino acids, whose first 25 amino acids function as a secretory signal peptide and which on removal yields the soluble 227 amino acid pro-OSM. Removal of the C-terminal most 31 amino acids produces the fully active 196 residue form. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Oncostatin M / OSM Protein (TMPY-02364) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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