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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-H2AX (Tyr143) Polyclonal Antibody

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货号 TMAB-10766

Anti-Phospho-H2AX (Tyr143) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-H2AX (Tyr143)。Anti-Phospho-H2AX (Tyr143) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-Phospho-H2AX (Tyr143) Polyclonal Antibody

Anti-Phospho-H2AX (Tyr143) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10766

Anti-Phospho-H2AX (Tyr143) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-H2AX (Tyr143)。Anti-Phospho-H2AX (Tyr143) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-H2AX (Tyr143) Polyclonal Antibody is a Rabbit antibody targeting Phospho-H2AX (Tyr143). Anti-Phospho-H2AX (Tyr143) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Chromosome.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human Histone H2AX around the phosphorylation site of Tyr143
抗原种属
Human
基因名称
H2AX
基因ID
3014
蛋白名称
Histone H2AX
Uniprot ID
P16104
功能
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
化学信息
分子量Theoretical: 16 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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