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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-AKT1 Monoclonal Antibody (3H509)

Synonyms: RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, CWS6, AKT
货号 TMAT-0048 一键复制产品信息
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Anti-AKT1 Monoclonal Antibody (3H509) 是一种 Mouse 抗体，靶向 AKT1。Anti-AKT1 Monoclonal Antibody (3H509) 可用于 WB,IF,FCM。

Anti-AKT1 Monoclonal Antibody (3H509)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0048

别名 RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, CWS6, AKT

Anti-AKT1 Monoclonal Antibody (3H509) 是一种 Mouse 抗体，靶向 AKT1。Anti-AKT1 Monoclonal Antibody (3H509) 可用于 WB,IF,FCM。

Anti-AKT1 Monoclonal Antibody (3H509)
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产品介绍

生物活性
产品描述
Anti-AKT1 Monoclonal Antibody (3H509) is a Mouse antibody targeting AKT1. Anti-AKT1 Monoclonal Antibody (3H509) can be used in WB,IF,FCM.
别名
RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, CWS6, AKT
Ig Type
IgG1
克隆号
3H509
反应种属
Human,Mouse,Monkey,Rat
应用WBIFFCM
推荐剂量
WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human AKT1 (AA: 1-150) expressed in E. Coli.
抗原种属
Human
基因名称
AKT1
基因ID
207
蛋白名称
RAC-alpha serine/threonine-protein kinase
Uniprot ID
P31749
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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