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Anti-IGF2/IGF-II Antibody (6S876)

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货号 TMAH-00600

别名 胰岛素样生长因子, Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2

Anti-IGF2/IGF-II Antibody (6S876) 是一种抗体,靶向 IGF2/IGF-II。Anti-IGF2/IGF-II Antibody (6S876) 可用于 ELISA。

Anti-IGF2/IGF-II Antibody (6S876)

Anti-IGF2/IGF-II Antibody (6S876)

一键复制产品信息
Rating icon 还可以
货号 TMAH-00600 别名 胰岛素样生长因子, Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2

Anti-IGF2/IGF-II Antibody (6S876) 是一种抗体,靶向 IGF2/IGF-II。Anti-IGF2/IGF-II Antibody (6S876) 可用于 ELISA。

规格价格库存数量
50 μL
¥ 1,315
5日内发货
100 μL
¥ 2,180
5日内发货
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产品介绍


生物活性
产品描述
Anti-IGF2/IGF-II Antibody (6S876) is an antibody targeting IGF2/IGF-II. Anti-IGF2/IGF-II Antibody (6S876) can be used in ELISA.
别名胰岛素样生长因子, Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2
Ig Type
Rabbit IgG
克隆号
6S876
反应种属
Human
应用ELISA
抗体种类
Monoclonal
亚细胞定位Secreted.
组织特异性Expressed in heart, placenta, lung, liver, muscle, kidney, tongue, limb, eye and pancreas.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human IGF2
抗原种属
Human
基因名称
IGF2
基因ID
Uniprot ID
研究领域
Signal Transduction
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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