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Anti-IGF2/IGF-II Antibody (6S876) 是一种抗体,靶向 IGF2/IGF-II。Anti-IGF2/IGF-II Antibody (6S876) 可用于 ELISA。
Anti-IGF2/IGF-II Antibody (6S876) 是一种抗体,靶向 IGF2/IGF-II。Anti-IGF2/IGF-II Antibody (6S876) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,315 | 5日内发货 | |
100 μL | ¥ 2,180 | 5日内发货 |
产品描述 | Anti-IGF2/IGF-II Antibody (6S876) is an antibody targeting IGF2/IGF-II. Anti-IGF2/IGF-II Antibody (6S876) can be used in ELISA. |
别名 | 胰岛素样生长因子, Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2 |
Ig Type | Rabbit IgG |
克隆号 | 6S876 |
交叉反应 | Human |
应用 | |
抗体种类 | Monoclonal |
亚细胞定位 | Secreted. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human IGF2 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Signal Transduction |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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