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Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody

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货号 TMAB-11039

Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-NFATc2 (Ser326)。Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody 可用于 FCM。

Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody

Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11039

Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-NFATc2 (Ser326)。Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NFATc2 (Ser326). Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse)
应用FCM
推荐剂量
FCM: 1-2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
组织特异性Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human NFATc2 around the phosphorylation site of Ser326
抗原种属
Human
基因名称
NFATC2
基因ID
4773
蛋白名称
Nuclear factor of activated T-cells, cytoplasmic 2
Uniprot ID
Q13469
功能
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.
化学信息
分子量Theoretical: 102 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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