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Anti-SAP/SH2D1A Antibody (9S143) 是一种 Mouse 抗体,靶向 SAP/SH2D1A。Anti-SAP/SH2D1A Antibody (9S143) 可用于 ELISA,ELISA(Det)。
Anti-SAP/SH2D1A Antibody (9S143) 是一种 Mouse 抗体,靶向 SAP/SH2D1A。Anti-SAP/SH2D1A Antibody (9S143) 可用于 ELISA,ELISA(Det)。
产品描述 | Anti-SAP/SH2D1A Antibody (9S143) is a Mouse antibody targeting SAP/SH2D1A. Anti-SAP/SH2D1A Antibody (9S143) can be used in ELISA,ELISA(Det). |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 9S143 |
交叉反应 | Human |
应用 | ELISA,ELISA(Det) |
推荐剂量 | ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SH2D1A ( 11149-H07ENP_002342.1Pro2-Lys97). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of a catalytic domain and the presence of an SH2domain suggest that SH2D1A regulates one or more signal transduction pathways. SH2D1A interacts with signaling lymphocytic activation molecule (SLAM), which is a transmembrane protein expressed on the surface of activated T and B cells. SH2D1A (SAP) interacts via its SH2domain with a motif (TIYXXV) present in the cytoplasmic tail of the cell-surface receptors, including CD150 / SLAM, CD84, CD229 / Ly-9, and CD244 / 2B4. SH2D1A was expressed in EBV-carrying, tumor phenotype representative (type I), but not in EBV-carrying lymphoblastoid cell line (LCL)-like (type III) or EBV-negative Burkitt lymphoma (BL) lines. It has been supposed to be related to the X-linked lymphoproliferative disease which is also known as Duncan's disease or Purtilo syndrome. |
偶联 | Unconjugated |
其他可选修饰符 | HRP |
可提供抗体种类 | 2 |
免疫原 | Recombinant Human SH2D1A Protein (TMPY-02440) |
抗原种属 | Human |
研究领域 | Adaptor Proteins |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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