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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CHRNA9 Polyclonal Antibody

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货号 TMAB-04332

Anti-CHRNA9 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CHRNA9。Anti-CHRNA9 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CHRNA9 Polyclonal Antibody

Anti-CHRNA9 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04332

Anti-CHRNA9 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CHRNA9。Anti-CHRNA9 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CHRNA9 Polyclonal Antibody is a Rabbit antibody targeting CHRNA9. Anti-CHRNA9 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein (Probable). Cell membrane; Multi-pass membrane protein (Probable).
组织特异性Expressed in cochlea, keratinocytes, pituitary gland, B-cells and T-cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. AChR alpha 9 is the only AChR found in cochlear hair cells. In adult rat cochlear outer hair cells (OHCs), AChR alpha 9 is expressed primarily in basal regions, where it is a component of the cholinergic receptor, while in inner hair cells (IHCs), it is expressed primarily in apical regions. The alpha 9 subunit mediates efferent synaptic transmission between cholinergic olivocochlear fibers and OHCs. One of the main functions of the AChR alpha 9 channel is to provide a pathway for calcium ion influx. AChR alpha 9 may also influence the arrival of efferent axons.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CHRNA9
抗原种属
Human
基因名称
CHRNA9
基因ID
55584
蛋白名称
Neuronal acetylcholine receptor subunit alpha-9
Uniprot ID
Q9UGM1
功能
CHRNA9 is a member of the ligand gated ionic channel family and nicotinic acetylcholine receptor superfamily. CHRNA9 forms homo- or hetero-oligomeric divalent cation channels. It is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.
化学信息
分子量Theoretical: 52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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