FOLR1 Protein, Human, Recombinant (hFc)

FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328.

规格	价格/CNY		数量
10 μg	￥ 430	现货
50 μg	￥ 1,320	5日内发货
500 μg	￥ 11,700	5日内发货
1 mg	￥ 17,600	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 430

现货

50 μg

￥ 1,320

5日内发货

500 μg

￥ 11,700

5日内发货

1 mg

￥ 17,600

5日内发货

生物活性	Loaded Human FOLR1-Fc on APS Biosensor, can bind Anti-Human FOLR1 mAb with an affinity constant of 0.11 nM as determined in BLI assay. (Regularly tested)
产品描述	FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328.

种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	P15328
别名	Folate receptor 1, Folate receptor, Folate receptor alpha, FOLR1, FR-alpha, Adult folate-binding protein, FR-α, Folate receptor α, Ovarian tumor-associated antigen MOv18, FBP
氨基酸序列	Arg25-Ser234
蛋白构建	Arg25-Ser234
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
分子量	55-75 kDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lung and cerebellum. The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor, or/and by proteolysis catalyzed by a metalloprotease. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. It has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. It is required for normal embryonic development and normal cell proliferation.

计算器

复溶计算器

重组蛋白稀释计算器

比活力计算器

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

bottom

FOLR1 Protein, Human, Recombinant (hFc)

计算器

技术支持

Keywords