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Anti-ASGR1 Polyclonal Antibody
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产品编号 TMAB-00153
Anti-ASGR1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ASGR1。Anti-ASGR1 Polyclonal Antibody 可用于 WB。
Anti-ASGR1 Polyclonal Antibody
Anti-ASGR1 Polyclonal Antibody
还可以产品编号 TMAB-00153
Anti-ASGR1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ASGR1。Anti-ASGR1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-ASGR1 Polyclonal Antibody is a Rabbit antibody targeting ASGR1. Anti-ASGR1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human,Rat (predicted:Mouse,Pig,Cow,Horse,Rabbit) |
| 验证活性 | Sample: Lane 1: Rat Liver tissue lysates Lane 2: Human HepG2 cell lysates Primary: Anti-ASGPR1 (TMAB-00153) at 1/200 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kDa Observed band size: 47 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:200-1000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | ASGR is a heterooligomeric receptor that is abundantly expressed on the sinusoidal surface of the hepatic plasma membrane. It is an endocytic receptor that rapidly binds and internalizes galactose-terminated glycoproteins (asialoglycoproteins or ASGP) from the circulation. The mouse ASGPR belongs to the long-form subfamily of the C-type/Ca2+ dependent lectin family. It is a complex of two noncovalently-linked and highly homologous subunits, a major 42 kDa glycoprotein ASGPR1(MHL-1) and a minor 51 kDa glycoprotein ASGR2 (MHL-2). ASGPR1 is synthesized as a type II transmembrane protein that contains a cytosolic N-terminal domain, a single transmembrane segment, and an extracellular domain which contains two important structural regions. The first is a stalk domain that contributes to noncovalent oligomerization, and the second is a Ca2+-dependent carbohydrate binding domain at the very C-terminus that is unusually stabilized by three ions. The aa sequence of mouse ASGPR1 ECD is 89% and 79% identical to the ASGPR1 ECD of rat and human, respectively. |
| 免疫原 | KLH conjugated synthetic peptide: human ASGPR1 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Organelle Proteins |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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