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Anti-PIK3R1 Antibody (5D427)

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产品编号 TMAH-00980
别名 PtdIns-3-kinase regulatory subunit p85-alpha, PtdIns-3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, GRB1

Anti-PIK3R1 Antibody (5D427) 是一种抗体,靶向 PIK3R1。Anti-PIK3R1 Antibody (5D427) 可用于 ELISA, IHC。

Anti-PIK3R1 Antibody (5D427)

Anti-PIK3R1 Antibody (5D427)

Rating icon 还可以
产品编号 TMAH-00980 别名 PtdIns-3-kinase regulatory subunit p85-alpha, PtdIns-3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, GRB1

Anti-PIK3R1 Antibody (5D427) 是一种抗体,靶向 PIK3R1。Anti-PIK3R1 Antibody (5D427) 可用于 ELISA, IHC。

规格价格库存数量
50 μL
¥ 1,310
5日内发货
100 μL
¥ 2,195
5日内发货
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产品介绍

生物活性
产品描述
Anti-PIK3R1 Antibody (5D427) is an antibody targeting PIK3R1. Anti-PIK3R1 Antibody (5D427) can be used in ELISA, IHC.
别名PtdIns-3-kinase regulatory subunit p85-alpha, PtdIns-3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, GRB1
Ig Type
Rabbit IgG
克隆号
5D427
交叉反应
Human
验证活性
1. IHC image of TMAH-00980 diluted at 1:50 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.63% DAB.
2. IHC image of TMAH-00980 diluted at 1:50 and staining in paraffin-embedded human rectal cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.63% DAB.
应用
ELISA, IHC
推荐剂量
IHC:1:50-1:200.
抗体种类
Monoclonal
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-d...
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human PIK3R1
抗原种属
Human
基因ID
5295
Uniprot ID
研究领域
Cancer, Immunology, Signal transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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