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Anti-Phospho-Tau (Ser202) Polyclonal Antibody

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货号 TMAB-11345

Anti-Phospho-Tau (Ser202) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Tau (Ser202)。Anti-Phospho-Tau (Ser202) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-Phospho-Tau (Ser202) Polyclonal Antibody

Anti-Phospho-Tau (Ser202) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11345

Anti-Phospho-Tau (Ser202) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Tau (Ser202)。Anti-Phospho-Tau (Ser202) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-Phospho-Tau (Ser202) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Tau (Ser202). Anti-Phospho-Tau (Ser202) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
组织特异性Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human Tau around the phosphorylation site of Ser202
抗原种属
Human
基因名称
MAPT
基因ID
蛋白名称
Microtubule-associated protein tau
Uniprot ID
功能
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
化学信息
分子量Theoretical: 52/79 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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