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Anti-NCR1 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 NCR1。Anti-NCR1 Polyclonal Antibody 3 可用于 WB。
Anti-NCR1 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 NCR1。Anti-NCR1 Polyclonal Antibody 3 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-NCR1 Polyclonal Antibody 3 is a Rabbit antibody targeting NCR1. Anti-NCR1 Polyclonal Antibody 3 can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Sheep) |
| 验证活性 | 1. Sample: Lane 1: Mouse Spleen tissue lysates Lane 2: Mouse Lung tissue lysates Lane 3: Rat Lymph node tissue lysates Lane 4: Human HL-60 cell lysates Primary: Anti-NCR1 (TMAB-09287) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 48 kDa 2. Sample: Kidney (Mouse) Lysate at 40 μg Spleen (Mouse) Lysate at 40 μg Lymph node (Mouse) Lysate at 40 μg A431 (Human) Cell Lysate at 30 μg Raji (Human) Cell Lysate at 30 μg Primary: Anti-NCR1 (TMAB-09287) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kD Observed band size: 46 kD |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Selectively expressed by both resting and activated NK cells. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. |
| 免疫原 | KLH conjugated synthetic peptide: human CD335 |
| 抗原种属 | Human |
| 基因名称 | NCR1 |
| 基因ID | |
| 蛋白名称 | Natural cytotoxicity triggering receptor 1 |
| Uniprot ID | |
| 功能 | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| 分子量 | Theoretical: 31 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |