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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TGF beta 1 Polyclonal Antibody

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货号 TMAB-01827

别名 转化生长因子, transforming growth factor, β1, transforming growth factor, beta 1, TGF β1

Anti-TGF beta 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TGF beta 1。Anti-TGF beta 1 Polyclonal Antibody 可用于 ELISA,WB。

Anti-TGF beta 1 Polyclonal Antibody

Anti-TGF beta 1 Polyclonal Antibody

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货号 TMAB-01827 别名 转化生长因子, transforming growth factor, β1, transforming growth factor, beta 1, TGF β1

Anti-TGF beta 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TGF beta 1。Anti-TGF beta 1 Polyclonal Antibody 可用于 ELISA,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-TGF beta 1 Polyclonal Antibody is a Rabbit antibody targeting TGF beta 1. Anti-TGF beta 1 Polyclonal Antibody can be used in ELISA,WB.
别名转化生长因子, transforming growth factor, β1, transforming growth factor, beta 1, TGF β1
Ig Type
IgG
反应种属
Human,Mouse
验证活性
25 μg total protein per Lane of various lysates probed with TGF Beta 1 polyclonal antibody, unconjugated (TMAB-01827) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
verifiedActivity
应用ELISAWB
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TGF-Beta 1
抗原种属
Human
基因名称
TGFB1
基因ID
7040
蛋白名称
Transforming growth factor beta-1 proprotein
Uniprot ID
P01137
研究领域
Response to hypoxia,TGF,Angiogenic growth factors,TGF,Co-factors,Hypoxia,tgf beta 1,TGF,Secreted
功能
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
化学信息
分子量Theoretical: 12.8/44 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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关键词

transforming growth factor, β 1transforming growth factor, b 1
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