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Anti-HTRA2 Antibody (2I343)

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货号 TMAB-07380

Anti-HTRA2 Antibody (2I343) 是一种 Rabbit 抗体，靶向 HTRA2。Anti-HTRA2 Antibody (2I343) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

Anti-HTRA2 Antibody (2I343)

Anti-HTRA2 Antibody (2I343)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07380

Anti-HTRA2 Antibody (2I343) 是一种 Rabbit 抗体，靶向 HTRA2。Anti-HTRA2 Antibody (2I343) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-HTRA2 Antibody (2I343) is a Rabbit antibody targeting HTRA2. Anti-HTRA2 Antibody (2I343) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Ig Type
IgG
克隆号
2I343
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIPIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IP: 1:20-50; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Mitochondrion intermembrane space. Mitochondrion membrane; Single-pass membrane protein (Potential). Note=Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.
组织特异性Isoform 1 is ubiquitous. Isoform 2 is expressed predominantly in the kidney, colon and thyroid.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
抗原信息
免疫原
A synthesized peptide: human HTRA2
抗原种属
Human
基因名称
HTRA2
基因ID
27429
蛋白名称
Serine protease HTRA2, mitochondrial
Uniprot ID
O43464
功能
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
化学信息
分子量Theoretical: 49 kDa. Actual: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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