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Anti-CD58 Antibody (8M86)

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产品编号 TMAY-02332

Anti-CD58 Antibody (8M86) 是一种 Mouse 抗体,靶向 CD58。Anti-CD58 Antibody (8M86) 可用于 FCM。

Anti-CD58 Antibody (8M86)

Anti-CD58 Antibody (8M86)

Rating icon 还可以
产品编号 TMAY-02332

Anti-CD58 Antibody (8M86) 是一种 Mouse 抗体,靶向 CD58。Anti-CD58 Antibody (8M86) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-CD58 Antibody (8M86) is a Mouse antibody targeting CD58. Anti-CD58 Antibody (8M86) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
克隆号
8M86
交叉反应
Human
验证活性
Flow cytometric analysis of Human CD58 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD58, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LFA-3 / CD58 (rh LFA-3 / CD58; TMPY-03489; AAH05930.1; Met1-Arg215). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
其他可选修饰符
PerCP/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Human LFA-3 / CD58 Protein (TMPY-03489)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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