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Anti-CD58 Antibody (8M86) 是一种 Mouse 抗体,靶向 CD58。Anti-CD58 Antibody (8M86) 可用于 FCM。
Anti-CD58 Antibody (8M86) 是一种 Mouse 抗体,靶向 CD58。Anti-CD58 Antibody (8M86) 可用于 FCM。
产品描述 | Anti-CD58 Antibody (8M86) is a Mouse antibody targeting CD58. Anti-CD58 Antibody (8M86) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 8M86 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human CD58 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD58, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
应用 | FCM |
推荐剂量 | FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LFA-3 / CD58 (rh LFA-3 / CD58; TMPY-03489; AAH05930.1; Met1-Arg215). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
其他可选修饰符 | PerCP/FITC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Human LFA-3 / CD58 Protein (TMPY-03489) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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