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IL-11 Protein, Cynomolgus, Recombinant (His)

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IL-11 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPK-00089

Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions. IL-11 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 20.48 kDa and the accession number is P20808.

IL-11 Protein, Cynomolgus, Recombinant (His)

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产品编号 TMPK-00089

规格	价格	库存
5 μg	¥ 358	6-8日内发货
10 μg	¥ 573	6-8日内发货
20 μg	¥ 938	5日内发货
50 μg	¥ 1,830	5日内发货
100 μg	¥ 3,100	5日内发货
200 μg	¥ 5,620	5日内发货
500 μg	¥ 12,400	5日内发货

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产品信息

生物活性	Human IL-11 R alpha, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus IL-11, His Tag with an affinity constant of 0.25 nM as determined in SPR assay.
产品描述	Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions. IL-11 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 20.48 kDa and the accession number is P20808.
种属	Cynomolgus
表达系统	HEK293 Cells
标签	N-His
蛋白编号	P20808
别名	白细胞介素,白介素,Oprelvekin,Interleukin-11,interleukin 11,INN: Oprelvekin,IL-11Oprelvekin,IL11,AGIF,Adipogenesis inhibitory factor
蛋白构建	Pro22-Leu199
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	20.48 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions.