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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BBS1 Polyclonal Antibody

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货号 TMAB-03033

Anti-BBS1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BBS1。Anti-BBS1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-BBS1 Polyclonal Antibody

Anti-BBS1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03033

Anti-BBS1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BBS1。Anti-BBS1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-BBS1 Polyclonal Antibody is a Rabbit antibody targeting BBS1. Anti-BBS1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell projection
组织特异性Highly expressed in the kidney. Also found in fetal tissue, testis, retina, adipose tissue, heart, skeletal muscle and pancreas.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
抗原信息
免疫原
KLH conjugated synthetic peptide: human BBS5
抗原种属
Human
基因名称
BBS1
基因ID
582
蛋白名称
Bardet-Biedl syndrome 1 protein
Uniprot ID
Q8NFJ9
功能
This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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