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Anti-ILK Antibody (7G881) 是一种 Rabbit 抗体,靶向 ILK。Anti-ILK Antibody (7G881) 可用于 WB,ICC/IF,IP,FCM。
Anti-ILK Antibody (7G881) 是一种 Rabbit 抗体,靶向 ILK。Anti-ILK Antibody (7G881) 可用于 WB,ICC/IF,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-ILK Antibody (7G881) is a Rabbit antibody targeting ILK. Anti-ILK Antibody (7G881) can be used in WB,ICC/IF,IP,FCM. |
| Ig Type | IgG |
| 克隆号 | 7G881 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBICC/IFIPFCM |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
| 组织特异性 | Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Integrin-linked kinases (ILKs) couple integrins and growth factors to downstream pathways involved in cell survival, cell cycle control, cell-cell adhesion and cell motility. ILK functions as a scaffold bridging the extracellular matrix (ECM) and growth factor receptors to the actin cytoskeleton through interactions with integrin, PINCH (which links ILK to the RTKs via Nck2), CH-ILKBP and affixin. |
| 免疫原 | A synthesized peptide: human ILK |
| 抗原种属 | Human |
| 基因名称 | ILK |
| 基因ID | |
| 蛋白名称 | Integrin-linked protein kinase |
| Uniprot ID | |
| 功能 | Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B. |
| 分子量 | Theoretical: 51 kDa. Actual: 51 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |