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Anti-TNFR2/CD120b/TNFR1B Antibody (2D734)

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Anti-TNFR2/CD120b/TNFR1B Antibody (2D734)
产品编号 TMAY-03123
别名 tumor necrosis factor receptor superfamily, member 1b, TNF-R-II, TNFR80, TNF-R75, TNFR2, TNFR1B, TNFBR, TBPII, p75TNFR, p75, CD120b

Anti-TNFR2/CD120b/TNFR1B Antibody (2D734) 是一种 Rabbit 抗体，靶向 TNFR2/CD120b/TNFR1B。Anti-TNFR2/CD120b/TNFR1B Antibody (2D734) 可用于 FCM。

Anti-TNFR2/CD120b/TNFR1B Antibody (2D734)
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Anti-TNFR2/CD120b/TNFR1B Antibody (2D734)

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Anti-TNFR2/CD120b/TNFR1B Antibody (2D734)
产品编号 TMAY-03123 别名 tumor necrosis factor receptor superfamily, member 1b, TNF-R-II, TNFR80, TNF-R75, TNFR2, TNFR1B, TNFBR, TBPII, p75TNFR, p75, CD120b

Anti-TNFR2/CD120b/TNFR1B Antibody (2D734) 是一种 Rabbit 抗体，靶向 TNFR2/CD120b/TNFR1B。Anti-TNFR2/CD120b/TNFR1B Antibody (2D734) 可用于 FCM。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-TNFR2/CD120b/TNFR1B Antibody (2D734) is a Rabbit antibody targeting TNFR2/CD120b/TNFR1B. Anti-TNFR2/CD120b/TNFR1B Antibody (2D734) can be used in FCM.
别名tumor necrosis factor receptor superfamily, member 1b, TNF-R-II, TNFR80, TNF-R75, TNFR2, TNFR1B, TNFBR, TBPII, p75TNFR, p75, CD120b
Ig Type
Rabbit IgG
克隆号
2D734
交叉反应
Mouse
验证活性
Flow cytometric analysis of Mouse TNFRSF1B (CD120b) expression on L929 cells. Cells were stained with purified anti-Mouse TNFRSF1B (CD120b), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TNFR2 / CD120b / TNFRSF1B (rM TNFR2 / CD120b / TNFRSF1B; TMPY-01697; NP_035740.2; Met1-Gly258).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFRSF1B is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. TNFR2/CD120b/TNFRSF1B is not a major contributing factor to the genetic risk of type 2 diabetes, its associated peripheral neuropathy and hypertension and related metabolic traits in North Indians. Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B) has been reported to be associated with SLE risk in Japanese populations. TNFR2/CD120b/TNFRSF1B serves as a receptor with high affinity for TNFSF2 and approximately 5-fold lower affinity for homotrimeric TNFSF1. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Mouse TNFR2 / CD120b / TNFRSF1B Protein (TMPY-01697)
抗原种属
Mouse
研究领域
Neuroinflammation
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

TNFR-80TNFR-2TNFR 80TNFR 2

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